Background
The Combination Pack CombiBreed Group 01 is assembled for dogs within the FCI Breedgroup 1, Sheepdogs and Cattle Dogs. This package covers several important traits and can be based on samples from animals at any age. Information on individual tests is available at our website.
This Combination Package contains the following markers:
• H306 Multifocal Retinopathy 3 (cmr3) 1
• H307 Multifocal Retinopathy 3 (cmr3) 2
• H324 FBN2
• H360 Gallbladder Mucocele
• H367 IGS (Selective Cobalamin Malabsorption) 2
• H414 Primary Ciliary dyskinesia
• H421 Hiplaxity 2
• H434 Dilated Cardiomyopathy (DCM)
• H484 CLAD, Type III
• H487 Brachyury (Bobtail)
• H489 Dermatofibrosis
• H498 Myotonia Congenita 2
• H677 Von-Willebrands Disease Type 1
• H721 Neuronal ceroid lipofuscinosis (NCL) 5
• H728 CSNB (Congenital Stationary Night Blindness)
• H745 X-SCID
• H748 Mucopolysaccharidosis Type VII
• H752 Gray Collie Syndrome (Cyclic Neutropenia)
• H770 rcd3 PRA
• H787 Trapped Neutrophil Syndrome (TNS)
• H809 Hereditary Cataract (HC) - HSF4
• H811 Hyperuricemia (HUU)
• H849 Primary Lens Luxation (PLL)
• H871 CMR1 (Canine Multifocal Retinopathy)
• H872 Pituitary dwarfism
• H915 gPRA
• H919 Hiplaxity 1
Test specific information
Dr. van Haeringen Laboratorium B.V. (VHL), introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
In addition to the strategy to introduce CombiBreed Combination Packages, we have compiled the packages by breed group and not for a specific breed.
Why CombiBreed packages per breed group?
• Our novel technology allows for logistical efficiency within our laboratory. This permits us to introduce the CombiBreed combination packages for a very competitive price.
• The CombiBreed packages contain DNA tests available in at least one breed within a breed group. Usually, scientific publications indicate if this genetic variation is validated for a breed.
• In our experience, the same genetic variation frequently occurs in closely related breeds, although the variation is only scientifically published in one breed. Mutations described and validated for a particular breed can thus also be present in other closely related breeds within a breed group. Laboratories performing these tests confirm the presence of mutations in other breeds.
• Our range of DNA tests will be reviewed several times per year. Newly available tests will be published on the website.
• We kindly request you to contact us (contactform) if your dog breed is not listed within a CombiBreed Group.
An actual overview of the genetic variation present in a breed can be assessed by performing the CombiBreed combination packages. Valuable information about previously unknown genetic variation may be found using our CombiBreed tests. However, ultimately our clients decide about the DNA tests ordered.
Age
Information on individual tests is elsewhere available on this website.
Turnaround time
The Turnaround Time (TAT) depends on various factors, such as the shipment time of your sample to the test location, the test method(s) and whether the tests are performed completely or partially by a Partner Lab or Patent owner.
The TAT of tests performed at our facilities is normally 10 working days after receipt of the sample at the testing laboratory (VHL, VHP or Certagen). For tests performed by a Partner Laboratory (so-called "partner lab test") or patent owner, the TAT is at least 20 working days after receipt of your sample. Because the shipment time to our Partner Labs or patent owner may vary due to factors we cannot influence, the mentioned 20 working days are therefore an estimate.
PLEASE NOTE
Sometimes it is necessary to re-run your sample. We call this a retest. In that case, the TAT will of course be extended.
Location of disease or trait
Information on individual tests is elsewhere available on this website.
Breed dependence
This DNA test is available for the following breeds: Australian Cattle Dog, Australian Shepherd, Australian Stumpy Tail Cattle Dog, Bearded Collie, Belgian Shepherd, Bobtail, Border Collie, Bouvier des Flandres, Briard, Cardigen Welsh Corgi, Collies, Czechoslovakian Wolfdog, German Shepherd, Kuvasz, Lancashire Heeler, Lapponian Herder, Miniature American Sheperd, Mudi, Old English Sheepdog, Pembroke Welsh Corgi, Polish Lowland Sheepdog (Polski Owczarek Nizinny - PON), Pyrenean Shepherd, Rough Collies, Saarloos Wolfhond, Schapendoes, Schipperke, Sheltie, Smooth Collies, Wäller, Welsh Corgi, White Swiss Shepherd Dog (Berger Blank Suisse). Additional information is available in the Frequently Asked Questions (FAQ).
Sample type
For this DNA test we accept the following materials: Blood EDTA, Blood Heparin, Swab, Semen, Tissue. Please contact Dr. Van Haeringen Laboratorium if you wish to submit other material as listed.
Result
Information on individual tests is elsewhere available on this website.
Inheritance
Information on individual tests is elsewhere available on this website.
Severity of Disease
Information on individual tests is elsewhere available on this website.