Certagen GmbH

H632 Coat Colour E-Locus 2

Background

During the last decades, a large number of scientific publications have described the genetic principles of coat colour and coat variation. Coat colours and coat variations are influenced by many hereditary factors. The DNA-tests are based on physiological effects in the body, in which the production and distribution of pigments result in many coat colour variants. In several cases, the coat colour of an animal may only be decided using DNA-tests. In each dog two pigments are the basis for their coat colour: black pigment (eumelanin) and red/yellow/cream pigment (pheomelanin). The production of black and red/yellow/cream pigment is controlled by the Melanocortin 1 Receptor (MC1R) gene, also known as Extension gene or E-Locus. The recessive e-variant is widespread in yellow and red-coloured dogs. By investigating cream-coloured Australian Cattle Dogs whose coat colour could not be explained by the e-variant, an additional variant, termed e2 was detected.

Test specific information

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Age

Most coat colours and coat types are usually visible directly after birth.

Turnaround time

The Turnaround Time (TAT) depends on various factors, such as the shipment time of your sample to the test location, the test method(s) and whether the tests are performed completely or partially by a Partner Lab or Patent owner.

The TAT of tests performed at our facilities is normally 10 working days after receipt of the sample at the testing laboratory (VHL, VHP or Certagen). For tests performed by a Partner Laboratory (so-called "partner lab test") or patent owner, the TAT is at least 20 working days after receipt of your sample. Because the shipment time to our Partner Labs or patent owner may vary due to factors we cannot influence, the mentioned 20 working days are therefore an estimate.

PLEASE NOTE
Sometimes it is necessary to re-run your sample. We call this a retest. In that case, the TAT will of course be extended.

Location of disease or trait

Genetic factors influencing coat colours and coat types are usually visible on the outside of an individual. Several factors may be hidden by the external variation.

Breed dependence

This DNA test is available for the following breeds: Australian Cattle Dog. Additional information is available in the Frequently Asked Questions (FAQ).

Sample type

For this DNA test we accept the following materials: Blood EDTA, Blood Heparin, Semen, Swab, Tissue. Please contact Dr. Van Haeringen Laboratorium if you wish to submit other material as listed.

Result

Coat colours and coat types are based on many genetic factors. For each factor, a separate test result will be returned.

Inheritance

Various genetic factors influencing coat colour and coat types are inherited in a dominant or recessive mode. Coat colours are influenced by a large number of genetic factors.

Severity of Disease

Factors influencing coat colour and coat types are usually not related to diseases.

Code H632

Coat Colour E-Locus 2

€ 48,12 (Incl. 16% VAT)
€ 41,48 (Excl. VAT)
Quantity