Thyroid follicular cell carcinomas (FCC) are mainly classified into four types: follicular thyroid carcinoma (FTC), papillary thyroid carcinoma (PTC), compact thyroid carcinoma (CTC), and follicular-compact thyroid carcinoma (FCTC). The upregulation of mitogen-activated protein kinase (MAPK) and phoshpatidylinositol-3-kinase (PI3K)/Akt signaling pathways was reported to cause the FCC in dogs and humans. The TPO gene was identified to be associated with FCC.
Clinical signs include the presence of cervical mass, intermittent cough, alopecia, polyuria, polydipsia, weight loss and lethargy.
Test specific information
This test is based on a genome wide association study which described two highly associated markers. Therefore, these markers are tested together.
The Turnaround Time (TAT) depends on various factors, such as the shipment time of your sample to the test location, the test method(s) and whether the tests are performed completely or partially by a Partner Lab or Patent owner.
The TAT of tests performed at our facilities is normally 10 working days after receipt of the sample at the testing laboratory (VHL, VHP or Certagen). For tests performed by a Partner Laboratory (so-called "partner lab test") or patent owner, the TAT is at least 20 working days after receipt of your sample. Because the shipment time to our Partner Labs or patent owner may vary due to factors we cannot influence, the mentioned 20 working days are therefore an estimate.
Sometimes it is necessary to re-run your sample. We call this a retest. In that case, the TAT will of course be extended.
Location of disease or trait
Trait or disease of the endocrine (hormone) system.
This DNA test is available for the following breeds: German Longhaired Pointer. Additional information is available in the Frequently Asked Questions (FAQ).
For this DNA test we accept the following materials: Semen, Swab, Tissue, Blood EDTA, Blood Heparin. Please contact Dr. Van Haeringen Laboratorium if you wish to submit other material as listed.
Severity of Disease