A mutation in the POMC gene was identified to body weight, or obesity. This gene produces a protein that tells the dog to stop eating when the body has eaten enough. Dogs with less of these proteins do not get this warning from the brain. Therefore they keep eating because the feeling of hunger doesn’t stop.
Test specific information
‘Early onset’ – This phrase indicates, that the symptoms of the disease can be detected at a lower age. ‘Early onset’ is the opposite of ‘late onset’, in which symptoms may be present at later ages. The phrases are used because the mutation causing ´early onset´ symptoms may be different compared to the mutations causing ´late onset´ symptoms.
The Turnaround Time (TAT) depends on various factors, such as the shipment time of your sample to the test location, the test method(s) and whether the tests are performed completely or partially by a Partner Lab or Patent owner.
The TAT of tests performed at our facilities is normally 10 working days after receipt of the sample at the testing laboratory (VHL, VHP or Certagen). For tests performed by a Partner Laboratory (so-called "partner lab test") or patent owner, the TAT is at least 20 working days after receipt of your sample. Because the shipment time to our Partner Labs or patent owner may vary due to factors we cannot influence, the mentioned 20 working days are therefore an estimate.
Sometimes it is necessary to re-run your sample. We call this a retest. In that case, the TAT will of course be extended.
Location of disease or trait
Trait or disease of diverse organs and tissues in the whole body.
This DNA test is available for the following breeds: Flat Coated Retriever, Labrador Retriever. Additional information is available in the Frequently Asked Questions (FAQ).
For this DNA test we accept the following materials: Blood EDTA, Blood Heparin, Tissue, Swab, Semen. Please contact Dr. Van Haeringen Laboratorium if you wish to submit other material as listed.
The disease is of multifactorial origin, which means that the symptoms are a result of the combination of genetic factors as well as the environment.
For each genetic factor of a multifactorial disease, a favourable allele exists. The results for this allele are inidcated as 'Normal'. Animals carrying one copy of the undesirable genetic variant are indicated as 'Carrier', whereas animals carrying two copies of the undesirable genetic variant are indicated as 'Affected'.
The disease is of multifactorial origin, which means that the symptoms are a combination of genetic factors as well as the environment.
Severity of Disease