Ocular squamous cell carcinoma (SCC) is the most common tumor of the eye in the horse. SCC is a slow growing cancer of the skin, mucous membranes and mucocutaneous junctions. Most commonly, the nictitating membrane, nasal canthus (nasal cavity), limbus (where the cornea meets the sclera) and eyelids are affected. Horses with less pigment in the skin surrounding their eyes (with white or pink eyelids) are at greater risk of developing SCC on their eyelids than horses with pigment around their eyes. Furthermore, horses with a chestnut-based coat colour appear to be at higher risk.
The prognosis for ocular SCC depends on several factors including the location and the size of the tumor. When a tumor is identified early, there is a good chance that the horse will be treated such that he or she can keep the eye. Horses with an extensive tumor may need to remove the eye in order to fully remove the tumor. When a tumor has already invaded the underlying bone, the prognosis for life is poor.
Test specific information
The Turnaround Time (TAT) depends on various factors, such as the shipment time of your sample to the test location, the test method(s) and whether the tests are performed completely or partially by a Partner Lab or Patent owner.
The TAT of tests performed at our facilities is normally 10 working days after receipt of the sample at the testing laboratory (VHL, VHP or Certagen). For tests performed by a Partner Laboratory (so-called "partner lab test") or patent owner, the TAT is at least 20 working days after receipt of your sample. Because the shipment time to our Partner Labs or patent owner may vary due to factors we cannot influence, the mentioned 20 working days are therefore an estimate.
Sometimes it is necessary to re-run your sample. We call this a retest. In that case, the TAT will of course be extended.
Location of disease or trait
This disease mainly affects vision, and may result in blindness.
This DNA test is available for the following breeds: Belgian, Haflinger, Percheron. Additional information is available in the Frequently Asked Questions (FAQ).
For this DNA test we accept the following materials: Blood EDTA, Blood Heparin, Hair, Semen, Tissue. Please contact Dr. Van Haeringen Laboratorium if you wish to submit other material as listed.
An animal can be free and has in that situation two healthy alleles. When used in breeding this animal will not become ill due to the disease. It cannot spread the disease in the population.
An animal can be carrier and has in that situation one healthy and one disease allele. When used in breeding 50 percent of the offspring will receive the disease allele. Carriers will not become ill.
An animal can be affected and has in that situation two disease alleles. When used in breeding all offspring will also receive the disease allele. Affected will become ill.
This genetic factor is inherited in an autosomal, recessive, mode. This means, that the individual can be free of the disease (homozygote normal), affected (homozygous affected) or carrier (heterozygous).
Carriers may spread the mutation in a population without showing symptoms themselves. Because of this, it is extremely important to identify carriers correctly to prevent spreading of a mutation.
Severity of Disease